Aerosol and solution for inhalation Berotek: instructions for use

Berotek belongs to the group of inhaled bronchodilator drugs.

Used to relieve attacks with bronchial asthma, obstructive bronchitis and other pulmonary diseases, accompanied by spasm of the bronchi. In some cases, it is prescribed for diagnostic tests in the study of the ability of the bronchi to expand.

On this page you will find all the information about Berotek: complete instructions for use for this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Berotec. Want to leave your opinion? Please write in the comments.

Clinico-pharmacological group

Bronchodilator drug - beta2-adrenomimetic.

Pharmacy sales terms

It is released on prescription.

Prices

How much is a berotek? The average price in pharmacies is 400 rubles.

Release form and composition

Berotek comes in the form of a clear, colorless solution for inhalation, free from particles and with an almost imperceptible odor.

  • The main active ingredient of the drug is fenoterol hydrobromide. 1 ml (20 drops) Berotec contains 1 mg of the active ingredient. Solution auxiliaries: sodium chloride, benzalkonium chloride, hydrochloric acid 1N, disodium edetate dihydrate and purified water.

Berotek is packed in amber glass dropper bottles of 20, 40 and 100 ml. In a cardboard bundle one bottle.

Pharmacological effect

The active component of Berotec has a bronchodilator effect, and also inhibits the release of inflammatory mediators from mast cells, thereby providing a protective effect against the effects of bronchoconstrictors such as methacholine, histamine, allergens and cold air.

The drug is used to relieve and prevent attacks of bronchospasm in bronchial asthma and other conditions that are accompanied by reversible airway obstruction, for example, in chronic obstructive bronchitis with or without emphysema.

Inhalation Berotek warn and effectively stop the bronchospasm of various origins in a short time - five minutes after inhalation.

Indications for use

Berotek, according to the instructions prescribed for the treatment of attacks of bronchial asthma or other conditions with reversible airway obstruction, including chronic obstructive pulmonary disease and chronic bronchitis.

Also inhalation Berotek apply:

  • When conducting bronchodilator tests conducted to study the function of external respiration;
  • For the prevention of attacks of bronchial asthma, which arose due to physical stress;
  • As a bronchodilator before inhalation with other drugs - mucolytics, antibiotics, glucocorticoids.

Contraindications

According to the instructions, Berotek is not appointed when:

  • Heart disease;
  • Thyrotoxicosis;
  • Decompensated diabetes;
  • Glaucoma;
  • Patient hypersensitivity to the drug;
  • Tachyarrhythmias;
  • Hypertrophic obstructive cardiomyopathy;
  • Aortic stenosis;
  • Threatening miscarriage, as well as in the first trimester of pregnancy.

According to the instructions, Berotek should be carefully prescribed for:

  • Severe diseases of the cardiovascular system;
  • Diabetes;
  • Hyperthyroidism;
  • Pheochromocytoma;
  • Recently suffered myocardial infarction.

Use during pregnancy and lactation

When using Berotec in pregnant women, there was no effect of this bronchodilator on the course of pregnancy. However, the effect of the drug (especially in the first trimester) does not exclude the effect on the uterus muscles.

In this regard, he is appointed to pregnant women only in cases where the expected benefit during therapy exceeds the risk for carrying pregnancy and fetal development.

Instructions for use

Home treatment may be recommended to patients after consulting a physician in cases when the use of low-dose high-speed bronchodilator beta-agonist (such as Berotec H) using a metered-dose aerosol was insufficient to alleviate the condition. It can also be recommended for patients in need of nebulizer therapy for other reasons, for example, in case of problems with the use of metered aerosols or, if necessary, the appointment of higher doses.

The instructions for use indicate that treatment with the drug Berotek should begin with the minimum recommended dose. It should be selected individually depending on the needs of the patient and adjusted according to the severity of the acute episode. The drug should be discontinued when sufficient relief is achieved.

Children under 6 years old (weighing less than 22 kg):

  • Due to limited information about this age group, treatment is carried out only under the supervision of a physician, prescribing the drug in the following dose: inhalation of about 50 μg / kg per reception (= 0.05 ml or 1 drop) / kg of body weight, but not more than 0.5 ml (10 drops) per dose up to 3 times / day.

Children aged 6 to 12 years (with a body weight of about 22-36 kg)

Asthma attacks and other conditions with reversible airway obstruction:

  • Assign inhalation 0.25-0.5 ml (5-10 drops = 250-500 μg of fenoterol hydrobromide), which in most cases is sufficient for immediate relief of symptoms; if necessary, re-appointment of the drug up to 4 times / day should consider the possibility of reducing the individual dose, depending on the effectiveness of the nebulizer.
  • AT severe cases(for example, in most cases of inpatient treatment), higher doses of 1 ml may be required (20 drops = 1000 μg of fenoterol hydrobromide).
  • ATexceptionally severe casesunder the supervision of a physician, the drug can be administered in a dose of up to 1.5 ml (30 drops = 1500 μg of fenoterol hydrobromide).

Prevention of bronchial asthma attacks due to physical stress:

  • Inject 0.5 ml (10 drops = 500 μg of fenoterol hydrobromide) before physical activity.

Adults (including patients over 75 years old) and adolescents over 12 years old

Attacks of bronchial asthma and other conditions accompanied by reversible airway obstruction:

  • Inhaled 0.5 ml is prescribed (10 drops = 500 µg of fenoterol hydrobromide), which in most cases is sufficient for immediate relief of the attack; if necessary, re-appointment of the drug up to 4 times / day should consider the possibility of reducing the individual dose, depending on the effectiveness of the nebulizer.
  • ATsevere cases (for example, for most patients entering the ICU) higher doses may be required - 1-1.25 ml (20-25 drops = 1000-1250 μg of fenoterol hydrobromide).
  • ATexceptionally heavy casesunder the supervision of a physician, doses up to 2 ml can be administered (40 drops = 2000 μg of fenoterol hydrobromide).

Prevention of bronchial asthma attacks due to physical stress:

  • Inject 0.5 ml (10 drops = 500 μg of fenoterol hydrobromide) before physical activity.

Treatment with Berotec is performed by inhalation using commercially available nebulizers. Pulmonary deposition and systemic bioavailability of the drug depend on the nebulizer used.

Note that 20 drops = 1 ml, 1 drop contains 50 μg of fenoterol hydrobromide. The recommended dose of the drug Berotek is diluted in a nebulizer chamber with a 0.9% sodium chloride solution to a final volume of 3-4 ml and inhaled to achieve sufficient relief of symptoms. Berotek can not be diluted with distilled water. The solution is diluted each time immediately before use; the remains of the prepared solution is poured.

Instructions for aerosol

Berotec Aerosol Dosage:

  • With an acute attack of bronchial asthma - 1 dose; inhalation can be repeated after 5 minutes. The next application of Beroteka is possible only after 3 hours.
  • In order to prevent asthma of physical effort and as a symptomatic treatment of conditions that are accompanied by reversible narrowing of the airways - 1-2 doses per dose (no more than 8 doses per day).

Side effects

When using the drug, including the use of high doses of the drug, the development of such side effects is possible:

  1. From the gastrointestinal tract: nausea, vomiting.
  2. From the central and peripheral nervous system: headache, dizziness, nervousness, irritability, weakness, convulsions. In isolated cases, mainly with long-term use of the drug, the development of mental changes is possible.
  3. Since the cardiovascular system: tachycardia, palpitations, increased systolic blood pressure, decreased diastolic blood pressure, angina, heart rhythm disturbances.
  4. Allergic reactions: skin rash, itching, urticaria, local inflammatory reactions, anaphylactic shock, angioedema.
  5. On the part of the respiratory system: cough, local irritation of the mucous membranes, paradoxical bronchospastic reactions.
  6. Other reactions: excessive sweating, myalgia, increased blood glucose levels.

In addition, the use of the drug can cause the development of severe hypokalemia, especially high risk of developing hypokalemia in patients with severe bronchial asthma, who receive therapy with glucocorticosteroids, diuretics and xanthine derivatives. With long-term drug therapy, as well as in patients receiving therapy with other drugs, should regularly monitor the level of potassium in the blood plasma.

With the development of side effects should consult your doctor.

Overdose

In case of overdose with a pharmaceutical preparation, the following symptoms are observed :;

  • hypertension or hypotension (depending on the patient's predisposition);
  • increase in pulse pressure;
  • intense redness of the skin of the face and upper half of the body;
  • tachycardia;
  • angina pain;
  • heartbeat;
  • arrhythmias;
  • angina attacks;
  • intentional tremor.

Special instructions

The balloon is designed for 200 inhalations. After that it needs to be replaced.

The tip should be kept clean. If necessary, it can be washed in warm water. After using detergent or soap, rinse thoroughly with clean water.

The contents of the container is under pressure. The cylinder must not be opened and subjected to heating above 50 ° C.

Dizziness may develop during treatment. Therefore, care should be taken when driving or using machinery.

Drug interactions

When prescribing, it is necessary to take into account drug interaction with other drugs:

  1. The combination of Berotec with β-adrenoreceptor blockers leads to a pronounced decrease in bronchodilation (expansion of the bronchial lumen);
  2. The simultaneous use of Berotec with β-adrenomimetics, anticholinergics, xanthine derivatives (including theophylline) stimulates the development of side effects;
  3. Simultaneous administration with halogenated hydrocarbon antiseptics (enflurane, halothane, etc.) enhances the influence of the active components of Berotec on the cardiovascular system;
  4. The overall therapeutic effect of Berotec is enhanced with simultaneous use with anticholinergics, tricyclic antidepressants, β-adrenoreceptor agonists, monoamine oxidase (MAO) enzyme inhibitors.

The therapeutic effect of conservative treatment of bronchial asthma and chronic obstructive pulmonary disease Berotek increases with its combined use with anti-inflammatory drugs (inhaled glucocorticosteroids). However, this treatment is recommended in the hospital for continuous monitoring of the patient.

Reviews

Reviews of Berotek indicate that the drug effectively relieves bronchospasm as in attacks of bronchial asthma, and in other diseases of the bronchopulmonary system. Patients note the long effect of this drug and its good tolerability.

In rare cases, there are side effects, the severity of which depends largely on the patient's health and the adequacy of the prescribed dose. Irritation of the oral mucosa, coughing and irritation when using this drug for the first time, as a rule, did not require the discontinuation of Berotec and passed on their own within a short period of time. Allergic reactions to the components of this bronchodilator were rarely detected.

Most patients appreciate the price of Beroteca as “affordable” and “acceptable.”

Analogs

Structural analogue of the drug is Berotec H, which is available as an aerosol for inhalation, as well as drugs Fenoterol, Aerum, Dosberotek, Segamol and Aruterol.

Before using analogues consult your doctor.

Storage conditions and shelf life

Berotek solution for inhalation is stored at a temperature of up to 30 ° C, in a dry place, protected from sunlight and inaccessible to children. Keep the product away from open flame, do not freeze. Shelf life is 5 years.

Do not use the drug after the expiration date on the package.

Watch the video: How to use Metered Dose Inhaler MDI (February 2020).

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